Patients experienced a median 57.6-month delay from first symptoms to ATTR-CM diagnosis, study finds. MITT and safety data show acoramidis significantly lowers AFib-related events in transthyretin cardiac amyloidosis. LuX-Valve offers a safe, effective option for severe TR patients at high surgical risk. ESC 2025: Acoramidis may reduce AF/flutter burden in ATTR-CM, per new ATTRibute-CM trial analysis discussed by CardioNerds. PVR severity is linked to higher short-term mortality in HFrEF, highlighting its role in risk stratification. IMPLEMENT-HF raised heart failure quad therapy use from 4.7% to 44.6% at discharge and 0% to 44.8% at 30 days. Experts call for better trials and teamwork to advance transcatheter valve treatment for heart failure-related valve disease. AI-driven ECGs are transforming heart failure care—enabling early detection, cutting costs, and expanding access. Checklist use for ATTR-CM "red flags" boosted diagnosis rates up to 10x in heart failure patients, study finds. Heart failure affects over 640,000 kids and teens globally—urgent prevention and care policies are needed, study finds. Waist-to-height ratio may better predict heart failure risk than BMI, new Heart Failure 2025 study finds. Acoramidis rapidly boosts serum TTR levels in ATTR-CM patients, with effects sustained through 30 months, study shows. Explore evolving LV unloading strategies in AMI shock with The CardioNerds. Pulmonary air embolism causing RV failure & arrest—via ocular route? A rare case, deep dive, with The CardioNerds. The presence of a CMP-PLP variant was linked to a 1.6-fold increased risk for cardiomyopathy or heart failure. Dr. Daniel Judge discusses how the ATTRibute-CM trial marks a turning point in ATTR cardiomyopathy treatment and research. Dr. Dan Judge speaks to The CardioNerds about his interpretation of the primary findings from ATTRibute-CM. Dr. Daniel Judge talks to the CardioNerds about a pivotal study in ATTR-CM. A multifaceted approach is necessary to reduce the deaths of smoking-related aortic aneurysms. Many preschool-aged children with congenital heart conditions are not on track for school readiness.