Iron Deficiency in HF: Data, Diagnosis & Insights

In this podcast episode, Drs. Amit Goyal, Jenna Skowronski, and Shazli Khan engage with Dr. Robert Mentz, Duke’s chief of heart failure, to explore iron deficiency in heart failure. Through a clinical case discussion, they detail diagnostic criteria, its high prevalence, and association with worse quality of life, hospitalizations, and mortality. The group reviews major trials—from FAIR‑HF and CONFIRM‑HF to IRONMAN and HEART‑FID—highlighting that intravenous, not oral, iron improves symptoms, exercise capacity, and potentially outcomes, with generally good safety. Moreover, the group discusses ESC guideline recommendations, practical outpatient surveillance and repletion strategies, and future research needs.

This podcast originally appeared on The CardioNerds.